Quick Answer: What Does High Alkaline Phosphatase Indicate?

Can osteoporosis cause elevated alkaline phosphatase?

Biver, et al.

has also showed raised levels of bone alkaline phosphatase in osteoporotic patients compared to normal, and these high levels may be associated with prevalent vertebral fractures..

Can vitamin D deficiency affect your liver?

Low vitamin D levels and bone disease are well-recognized complications of “cholestatic” liver disease, which decreases the production or flow of bile. More recently, studies have confirmed low vitamin D levels in noncholestatic liver disease.

Can vitamin D deficiency cause elevated alkaline phosphatase?

Thus, vitamin D deficiency is usually accompanied by normal blood levels for calcium and phosphorus, high-normal or elevated levels of PTH, normal to elevated levels of total alkaline phosphatase, a low 24-hour urine calcium excretion rate, and low levels of total 25(OH)D.

Is 60 a high ALT level?

Upper limits of normal range from 30 IU/L to 60 IU/L, depending on the laboratory. “We want to reset it southward of 30 IU/L,” Dr. DiBisceglie said. “ALT levels are a reflection of the general vascular condition,” he said.

When should I worry about Alt?

A low level of ALT in the blood is expected and is normal. Liver disease is the most common reason for higher than normal levels of ALT. Very high levels of ALT (more than 10 times normal) are usually due to acute hepatitis, sometimes due to a viral hepatitis infection.

What are the symptoms of high alkaline phosphatase?

Why do I need an alkaline phosphatase test?Nausea and vomiting.Weight loss.Tiredness.Weakness.Jaundice, a condition that causes your skin and eyes to turn yellow.Swelling and/or pain in your abdomen.Dark-colored urine and/or light-colored stool.Frequent Itching.

What is considered high alkaline phosphatase?

The ALP level in healthy adults should be 20–140 units per liter (U/L). Children tend to have significantly higher levels of ALP than adults because their bones are still growing. A person recovering from a bone injury may also have a raised ALP level in the 3 months after the injury while their bone heals.

How can I lower my alkaline phosphatase levels?

Make changes to your dietavoid fruits and vegetables served with high-calorie sauces or added sugar and salt.eat fish at least twice a week, ideally those high in omega-3 fatty acids, such as salmon or trout.opt for fat-free or low-fat milk and dairy products.More items…•

Can high alkaline phosphatase cause itching?

Itching sometimes gets worse during pregnancy or if you’re undergoing hormone replacement therapy. Serum alkaline phosphatase (ALP). People with itch related to liver disease may have elevated ALP.

Where do you itch with liver problems?

According to a 2017 article, healthcare professionals commonly associate itching with chronic liver disease, especially cholestatic liver diseases, such as PBC and primary sclerosing cholangitis (PSC). The itching typically occurs on the soles of the feet and the palms of the hands.

Is Alt 52 high?

Alanine aminotransferase (ALT) is an enzyme found mainly in the liver. High levels (>50) indicate damage to liver cells as a result of infection (hepatitis, infectious mononucleosis, etc.) or toxic levels of drugs (e.g. acetaminophen [Tylenol]) or chemicals (e.g. chloroform) or alcohol.

Is 70 a high ALT level?

Normal Lab Values The normal levels vary based on a person’s body mass index (BMI) as well as the individual lab’s reference value. Generally speaking, the normal reference value for adults is: AST: 8 to 48 IU/L. ALT: 7 to 55 IU/L.

What drugs increase alkaline phosphatase?

The following drugs may affect the level of alkaline phosphatase in the blood:Allopurinol.Antibiotics.Anti-inflammatory medicines.Birth control pills.Certain diabetes medicines.Chlorpromazine.Cortisone.Male hormones.More items…•

What do you do if your alkaline phosphatase is high?

Higher-than-normal levels of ALP in your blood may indicate a problem with your liver or gallbladder. This could include hepatitis, cirrhosis, liver cancer, gallstones, or a blockage in your bile ducts.

What are the first signs of liver damage from alcohol?

Generally, symptoms of alcoholic liver disease include abdominal pain and tenderness, dry mouth and increased thirst, fatigue, jaundice (which is yellowing of the skin), loss of appetite, and nausea. Your skin may look abnormally dark or light. Your feet or hands may look red.

What is the normal range for alkaline phosphatase levels?

Normal Results The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex.

What foods are high in alkaline phosphatase?

Certain food groups are considered acidic, alkaline, or neutral:Acidic: meat, poultry, fish, dairy, eggs, grains, alcohol.Neutral: natural fats, starches, and sugars.Alkaline: fruits, nuts, legumes, and vegetables.

What bone disorders cause elevated alkaline phosphatase?

Bone pathology causes of elevated alkaline phosphatase include Paget’s disease, hyperparathyroidism, osteomalacia, metastatic bone disease and a recent fracture.

Can arthritis cause high alkaline phosphatase?

Increased concentration of serum alkaline phosphatase (ALP) is a common feature in rheumatoid arthritis (RA), although its origin remains unclear.

What are signs that your liver is not functioning properly?

If signs and symptoms of liver disease do occur, the may include: Skin and eyes that appear yellowish (jaundice) Abdominal pain and swelling. Swelling in the legs and ankles.