What Is Considered A High CEA Level?

How accurate is a CEA blood test?

Of the 582 patients undergoing CEA follow-up, 104 (17.9%; 95% CI: 15.0% to 21.2%) developed a recurrence during the 5-year follow-up period….Table 1.Final CEA measurement (95% CI)All CEA measurements (95% CI)Sensitivity49.0% (39.2–59.0%)50.0% (40.1–59.9%)Specificity97.5% (95.5–98.6%)93.3% (90.6–95.3%)4 more rows•Mar 10, 2017.

Does high CEA levels mean cancer?

A high level of CEA can be a sign of certain types of cancers. These include cancers of the colon and rectum, prostate, ovary, lung, thyroid, or liver. High CEA levels may also be a sign of some noncancerous conditions, such as cirrhosis, noncancerous breast disease, and emphysema.

Can CEA levels fluctuate?

Serum CEA levels fluctuate over time in healthy individuals, and the intraindividual variation has been reported to be about 30% [19].

What is a dangerous CEA level?

Levels of CEA higher than 20 ng/mL are considered very high. If you have CEA levels this high and you also have symptoms of cancer, it strongly suggests the cancer has not been removed successfully after treatment. It may also suggest that the cancer has metastasized, or spread, to other parts of your body.

What kind of cancer does CEA detect?

The carcinoembryonic antigen (CEA) test may be used: To monitor the treatment of colon cancer—it may also be used as a marker for medullary thyroid cancer and cancers of the rectum, lung, breast, liver, pancreas, stomach, and ovaries.

Does CEA increase with age?

In both nonsmokers and smokers, CEA levels increased with age. related to age in smokers and non- smokers. their higher mean age (Table 1).

What is considered a high CA 125 level?

CA-125 blood test results can vary depending on the laboratory that performed the analysis. In most instances, however, CA-125 levels are considered elevated if they are above 35 units per milliliter. Certain cancer medications and surgeries can also alter CA-125 levels.

What is a normal CEA level in colon cancer?

CEA is an antigen (small protein) that is found on the surface of many types of cancer cells and high levels of CEA can be detected in the blood of some patients with cancer and the developing fetus. The CEA is measured in the blood and the normal range is <2.5 ng/ml in an adult non-smoker and <5.0 ng/ml in a smoker.

What is the normal range for cancer markers?

Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.

What is a high CA 125 level?

Eventually, a CA 125 level of 35 units was found to be a useful cutoff point, with 99% of healthy women having values less than 35. Levels above 35 units are certainly seen in healthy women, but beyond the cutoff point of 35, the higher the value, the more likely there is trouble somewhere in the body.

Can stress raise CEA levels?

Discussion. Our findings clearly indicated that immobilization stress results in enhanced serum CEA level whether the stress is acute or chronic. Consistent with our finding, there are reports suggesting that stress can increase tumor growth and tumor marker expression [26, 27].

How reliable are tumor markers?

There has been no evidence to prove that tumor markers are 100 percent reliable for determining the presence or absence of cancer. Many circumstances, such as other health issues or disease, can contribute to raised tumor marker levels.

What is a high cancer marker?

What are tumor markers? Tumor markers are substances found in higher-than-normal levels in the blood, urine, or tissues of some people with cancer. These substances, which are also called biomarkers, can be made by the tumor. They can also be made by healthy cells in response to the tumor.

What is the normal range for CEA blood levels?

Normal Results The normal range is 0 to 2.5 ng/mL (0 to 2.5 µg/L). In smokers, slightly higher values may be considered normal (0 to 5 ng/mL, or 0 to 5 µg/L).

How often should CEA test be done?

CEA test. This is a blood test that detects the levels of CEA protein. High levels of CEA may indicate that a cancer has spread to other parts of the body. CEA testing is recommended every three to six months for five years.